Elm Street Ventures is a New Haven, Connecticut-based seed and early-stage venture capital firm that backs technology and life sciences startups, especially those developing cutting-edge research with commercial potential and often originating from Yale University and other Connecticut institutions. Founded in 2006 with strong ties to Yale’s scientific and entrepreneurial ecosystem, the firm typically invests initial capital in nascent companies and may participate in follow-on rounds as ventures progress toward market traction. Its investment focus spans therapeutics, diagnostics, research tools, materials science, climate tech and other deep-technology sectors where academic innovation intersects with commercial application. Elm Street emphasizes supporting founders and scientific teams through strategic guidance, recruitment and business development alongside capital deployment. The firm’s portfolio reflects selective engagement in science-driven startups that require early institutional backing to bridge research and scalable venture growth.