Two River is a United States-based life sciences venture creation and investment firm headquartered in New York. The firm focuses on founding, building, and financing biotechnology companies, partnering closely with scientific founders and experienced management teams. It invests its own capital into companies with strong intellectual property across areas such as oncology, immunotherapy, and synthetic biology. Two River provides capital alongside deep operational involvement, including support in product development, regulatory strategy, and leadership recruitment. Its model centers on actively building companies from inception through clinical development to improve patient outcomes.