Route 66 Ventures, LLC is a U.S. venture capital firm based in Alexandria, Virginia (Washington D.C. metropolitan area, Northern Virginia), investing in digital-health and financial-services / fintech companies. The firm's name ''Route 66'' references the iconic historic U.S. federal highway (Chicago to Santa Monica), a distinctive Americana-heritage branding choice. The firm was founded by partners with backgrounds in financial services and operates as a Washington D.C. / Northern Virginia regional specialist investor. Route 66 has raised multiple institutional funds with aggregate AUM in the USD low-to-mid hundreds of millions range, typically writing initial check sizes in the USD 1 to 10 million range at Series A and Series B stages. Notable portfolio companies have included various digital-health, fintech, and adjacent technology companies in the D.C. metropolitan corridor and broader U.S. East Coast markets. Detailed current aggregate AUM, fund-vintage disclosures, and comprehensive portfolio-company disclosures are partially documented in mainstream financial-industry databases for this specific URL.