Plains VC is an Oklahoma City-based venture capital firm backing seed and Series A companies in overlooked U.S. markets between the coasts. The firm focuses on software, SaaS, life sciences, biotechnology, advanced materials and manufacturing, with additional healthtech and medical-device investment exposure. It typically invests $250K to $1M and provides capital, guidance, co-investment support, diligence, strategy support and network access for founders seeking early-stage venture backing.