Pillar VC is a Boston-based venture capital firm that invests at the pre-seed and seed stages in technically ambitious founders building science- and technology-driven companies. It typically invests between $50,000 and $7 million, with an average check of approximately $2.5 million, and works closely with founders from company formation through early growth. Relevant sectors include artificial intelligence, biotechnology, healthcare, advanced computing, enterprise software, manufacturing, consumer technology and crypto/Web3. The firm has a particular focus on scientific founders, university spinouts and breakthrough technologies. Portfolio companies include Abridge, Ginkgo Bioworks, Circle, Latent Labs, Portal Biotech and Everyrealm.