ONCE Ventures is a venture capital firm investing in consumer health companies across North America, with observed U.S. Series A activity. It focuses on longevity, microbiome, personalized nutrition, mental wellness, women's health and other scientifically differentiated health products, spanning HealthTech, wellness, life sciences, nutrition and digital health. The firm typically targets Series A and B companies and invests up to $5 million, with select earlier or later-stage opportunities when there is strong strategic fit.