Mansueto Investments is the private investment arm of Mansueto Office, a Chicago-based family-office investment platform that backs private companies in the United States. It invests at early-stage venture rounds, including Series A financings, with portfolio exposure across life sciences, biotechnology, pharmaceuticals, healthtech, medical devices, nutrition, food technology, SaaS, data and media. Portfolio companies include AgileMD, Endotronix, Pyxis Oncology, Syntis Bio and Tovala.