IllinoisVENTURES is a U.S. university-technology-transfer-focused seed and early-stage venture capital firm headquartered in Chicago, Illinois, affiliated with the University of Illinois system and focused on research-derived commercialisation investments in companies spun out of University of Illinois (Urbana-Champaign / UIUC, Chicago / UIC, Springfield) research labs, Argonne National Laboratory, Fermi National Accelerator Laboratory (Fermilab), and other Midwest-U.S. federal research institutions and universities. The firm invests in information technology (computer science / AI / cybersecurity), physical sciences (clean energy, materials, advanced manufacturing, semiconductors, robotics), and life sciences (biotechnology, medical devices, diagnostics) at pre-seed and seed stages with typical initial check sizes in the USD 100,000 to USD 2 million range. IllinoisVENTURES has deployed capital across multiple fund vintages with a distinctive focus on commercialising deep-science research emerging from its affiliated universities and national labs. The firm is part of the broader Illinois innovation-ecosystem including the University of Illinois Research Park, Chicago's 1871 and MATTER incubators, and state-level initiatives such as the Illinois Growth and Innovation Fund.