Cascade Investment is a Kirkland, Washington-based family office and private investment firm managing assets associated with Bill Gates and the Gates Foundation Trust. It uses a long-horizon, value-oriented approach across asset classes and global markets, with exposure to real estate, agriculture, aviation, transportation and travel, and has backed private companies and venture-related funds. Its venture activity includes early- and later-stage investments in biotechnology, life sciences and environmental sectors such as waste management and water.