John R. Oishei Foundation (Oishei Foundation) is an independent non-profit private foundation based in Buffalo, New York. Established in 1940, the foundation seeks to enhance the economic vitality and quality of life for the Buffalo Niagara region through grantmaking, leadership, and network building. Additionally, it supports education, scientific research, health care, cultural, social, and civic needs of the Buffalo community. The investment funds of the foundation are managed by the board of directors.John R. Oishei Foundation's investment portfolio is valued at $260.92 million, with investments in private equity and cash.